Dentist info: peripheral giant cell Granuloma
Peripheral giant cell Granuloma (Granuloma Peripheral giant cell) is best known as giant cell epulis is a tumor similar condition that usually develops from the free edge of the gums. The term peripheral giant cell Granuloma preferable reparatif Granuloma peripheral giant cell. This lesion was found in all age groups, with the highest incidence peak in adults aged 30 years and the children’s teeth during mixing.
In the research material consisted of 173 people with peripheral giant cell Granuloma, found that the level of disease is highest in the period of mixed teeth. In childhood Granuloma is more common in boys than girls, after 16 years of age affected the number of women are two times the number of men affected. Mandible slightly more often affected than the maksilla and more common in the premolar-molar region than in the incisivus-caninus. Sometimes, the lesions found in the edentulous alveolar ridge.
Peripheral giant cell Granuloma has an unknown aetiology, with some debate whether these lesions showed a reactive process or neoplastic. Nevertheless, most experts believe that the giant cell Granuloma peripheral including a reactive lesion.
Granuloma peripheral giant cell lesions including reactive rare. This lesion is also known as giant-cell epulis, osteoclastoma, giant cell reparative giant cell Granuloma or myeloid hyperplasia and epulis. Granuloma peripheral giant cell lesions including giant cell is most common in the jaw and from the connective tissue of the periosteum or periodontal membrane, in response to local irritation or chronic trauma.
Definition Granuloma Peripheral Giant Cell
Peripheral giant cell Granuloma is ekstraosseus nodules consisting of proliferation of mononuclear and giant cell multinukleasi related vaskularisasi found on the gingiva or alveolar ridge.
Peripheral giant cell Granuloma is a hyperplastic reaction in the gingival tissue is dominated by components and endothelial cell histiositik. Both types of cells are mixed and arranged in lobular pattern separated by fibrous connective tissue containing blood vessels large sinusoids.
The name is taken from the lesion histiosit tendency to form giant mononuclear cell multinukleasi broad; peripheral location (ekstraosseus) of these lesions is more narrow, more likely to center (intraosseus); and clinical picture of the gingival lesions is similar to the response to the reactive Granuloma.
The factors that initiate the occurrence of lesions is unknown. Lesions containing giant cell networks similar to those found in other parts of the body but primarily in the bone.
Causes (Etilogy) Granuloma Peripheral Giant Cell
Granuloma Causes of peripheral giant cell is unknown, although local irritation caused by dental plaque or calculus, periodontal disease, tooth restoration bad, bad protesa, or extract a tooth, has been considered to participate in the development of these lesions.
Research recently, describes the development of giant cell Granuloma-related peripheral dental implants. Peripheral giant cell Granuloma emerged as a result of unusual complication of implant placement, developed from several months to several years after placement of dental implants.
Clinical picture of Giant Cell Granuloma Peripheral
Lesion begins with swelling of colored dome-shaped reddish or purple-colored on the interdental papilla or the alveolar ridge. Dentulous lesions in patients often look more reddish due to ulceration happens when food is chewed and the thin epithelium of the mass protruding.
Larger lesions are usually around one or more teeth, often involving the periodontal ligament, including the apex of the tooth. These lesions cause loss and movement of teeth. Edentulous area lesions on the dome-shaped, purple, and usually have an intact surface. Periapikal radiographs generally show a loss of superficial layers of the cortical bone, and the remaining bones in the middle who do not get involved.
Peripheral giant cell Granuloma is characterized by a clear boundary swelling, hard, and rarely berulserasi. Basically not stemmed, the surface smooth or slightly bergranula and pink to purple red. Nodula are usually several mm to 1 cm in diameter, although the rapid enlargement can create a disturbing large growth in the teeth beside him. The lesions are usually without symptoms, tatapi because of its aggressive, then the alveolar bone below it are often involved and make radiolusensi “peripheral cuff” patognomonik superficial.
Histopathology Granuloma Peripheral Giant Cell
Microscopic picture showing nodular structure of giant cell networks are separated by fibrous septum. Networking giant cell consists of a mixture of mononuclear and giant cell multinukleasi underlying ekstravasasi red blood cells. There are a number of capillaries and the sinusoids. Fibrous stroma thinned or thickened, and contains a wide network and the structure of the thin vascular walls. Hemosiderin content of large amounts of tissue are found in and around giant cell fibrous components.
Histologically found many beriti multiple giant cells and fibroblast-fibroblast in all specimens. Histologically, these lesions can not be distinguished from central giant cell Granuloma and brown tumors of hyperparathyroidism.
Diagnosis of Giant Cell Peripheral Appeal
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Posted: February 16th, 2010 under Dental Care and Oral Health.
Tags: Dentist info: peripheral giant cell Granuloma, Dentulous, Edentulous, Giant Cell, Granuloma, Hemosiderin, hyperparathyroidism, vascular
